Physiological Mouse Brain Aβ Levels Are Not Related to the Phosphorylation State of Threonine-668 of Alzheimer's APP

BACKGROUND: Amyloid-β peptide species ending at positions 40 and 42 (Aβ40, Αβ42) are generated by the proteolytic processing of the Alzheimer's amyloid precursor protein (APP). Aβ peptides accumulate in the brain early in the course of Alzheimer's disease (AD), especially Aβ42. The cytopla...

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Main Authors: Sano, Yoshitake, Nakaya, Tadashi, Pedrini, Steve, Takeda, Shizu, Iijima-Ando, Kanae, Iijima, Koichi, Mathews, Paul M., Itohara, Shigeyoshi, Gandy, Sam, Suzuki, Toshiharu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2006
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762327/
https://ncbi.nlm.nih.gov/pubmed/17183681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000051
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