A Proof-Of-Principle Study of Epigenetic Therapy Added to Neoadjuvant Doxorubicin Cyclophosphamide for Locally Advanced Breast Cancer

BACKGROUND: Aberrant DNA methylation and histone deacetylation participate in cancer development and progression; hence, their reversal by inhibitors of DNA methylation and histone deacetylases (HDACs) is at present undergoing clinical testing in cancer therapy. As epigenetic alterations are common...

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Hauptverfasser: Arce, Claudia, Pérez-Plasencia, Carlos, González-Fierro, Aurora, de la Cruz-Hernández, Erick, Revilla-Vázquez, Alma, Chávez-Blanco, Alma, Trejo-Becerril, Catalina, Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucia, Bargallo, Enrique, Villarreal, Patricia, Ramírez, Teresa, Vela, Teresa, Candelaria, Myrna, Camargo, Maria F., Robles, Elizabeth, Dueñas-González, Alfonso
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2006
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762324/
https://ncbi.nlm.nih.gov/pubmed/17183730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000098
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