Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture.

Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma cruzi both in vitro and in some clinical models. Heretofore they have not been effective against the African trypanosomes; this suggested that these organisms were not compa...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Fish, W R, Marr, J J, Berens, R L, Looker, D L, Nelson, D J, LaFon, S W, Balber, A E
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1985
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3985595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.1.33
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