Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture.

Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma cruzi both in vitro and in some clinical models. Heretofore they have not been effective against the African trypanosomes; this suggested that these organisms were not compa...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Fish, W R, Marr, J J, Berens, R L, Looker, D L, Nelson, D J, LaFon, S W, Balber, A E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3985595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.1.33
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