Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture.

Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma cruzi both in vitro and in some clinical models. Heretofore they have not been effective against the African trypanosomes; this suggested that these organisms were not compa...

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Detaylı Bibliyografya
Asıl Yazarlar: Fish, W R, Marr, J J, Berens, R L, Looker, D L, Nelson, D J, LaFon, S W, Balber, A E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1985
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC176200/
https://ncbi.nlm.nih.gov/pubmed/3985595
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