Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture.

Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma cruzi both in vitro and in some clinical models. Heretofore they have not been effective against the African trypanosomes; this suggested that these organisms were not compa...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Fish, W R, Marr, J J, Berens, R L, Looker, D L, Nelson, D J, LaFon, S W, Balber, A E
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1985
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3985595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.1.33
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