Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture.

Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma cruzi both in vitro and in some clinical models. Heretofore they have not been effective against the African trypanosomes; this suggested that these organisms were not compa...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Fish, W R, Marr, J J, Berens, R L, Looker, D L, Nelson, D J, LaFon, S W, Balber, A E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1985
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3985595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.1.33
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