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Mechanism of hERG K(+) channel blockade by the fluoroquinolone antibiotic moxifloxacin
1. The fluoroquinolone antibiotic moxifloxacin has been associated with the acquired long QT syndrome and is used as a positive control in the evaluation of the QT-interval prolonging potential of new drugs. In common with other QT-prolonging agents, moxifloxacin is known to inhibit the hERG potassi...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1760709/ https://ncbi.nlm.nih.gov/pubmed/16474415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706678 |
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