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Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652

1. Pharmacological blockade of the Human ether-a-go-go related gene (HERG) potassium channel is commonly linked with acquired long QT syndrome and associated proarrhythmia. The objectives of this study were (i) to identify and characterise any inhibitory action on HERG of the selective-serotonin re-...

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Detalhes bibliográficos
Main Authors: Milnes, James T, Crociani, Olivia, Arcangeli, Annarosa, Hancox, Jules C, Witchel, Harry J
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573929/
https://ncbi.nlm.nih.gov/pubmed/12839862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705335
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