Antimalarial activity of a combination of 5-fluoroorotate and uridine in mice.
Malarial parasites, in contrast to mammalian cells, utilize orotic acid more efficiently than uracil or uridine. Recently, chloroquine-susceptible and chloroquine-resistant clones of Plasmodium falciparum were shown to be inhibited by 5-fluoroorotate, with a 50% inhibitory concentration of 6 nM in v...
-д хадгалсан:
| -д хэвлэсэн: | Antimicrob Agents Chemother |
|---|---|
| Үндсэн зохиолчид: | , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
American Society for Microbiology (ASM)
1990
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| Нөхцлүүд: | |
| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2386369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.7.1371 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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