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Selection and characterization of 5-fluoroorotate-resistant Plasmodium falciparum.

Previous studies have shown that 100 nM 5-fluoroorotate (5-FO) is sufficient to block the in vitro proliferation of Plasmodium falciparum without causing toxicity to mammalian cells. In anticipation of potential drug resistance, a study was undertaken to identify P. falciparum cells that would proli...

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Detalles Bibliográficos
Main Authors: Rathod, P K, Khosla, M, Gassis, S, Young, R D, Lutz, C
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC188299/
https://ncbi.nlm.nih.gov/pubmed/7695275
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