Selection and characterization of 5-fluoroorotate-resistant Plasmodium falciparum.

Previous studies have shown that 100 nM 5-fluoroorotate (5-FO) is sufficient to block the in vitro proliferation of Plasmodium falciparum without causing toxicity to mammalian cells. In anticipation of potential drug resistance, a study was undertaken to identify P. falciparum cells that would proli...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Rathod, P K, Khosla, M, Gassis, S, Young, R D, Lutz, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.12.2871
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