Molecular characterization of murine humoral immune response to botulinum neurotoxin type A binding domain as assessed by using phage antibody libraries.

To produce antibodies capable of neutralizing botulinum neurotoxin type A (BoNT/A), the murine humoral immune response to BoNT/A binding domain (H(C)) was characterized at the molecular level by using phage antibody libraries. Mice were immunized with BoNT/A H(C), the spleens were harvested, and sin...

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Bibliografiske detaljer
Main Authors: Amersdorfer, P, Wong, C, Chen, S, Smith, T, Deshpande, S, Sheridan, R, Finnern, R, Marks, J D
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC175534/
https://ncbi.nlm.nih.gov/pubmed/9284147
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