Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy

Background: Gene therapy of the joint has great potential as a new therapeutic approach for the treatment of rheumatoid arthritis (RA). The vector chosen is of crucial importance for clinical success. Objective: To investigate the tropism and transduction efficiency in arthritic joints in vivo, and...

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Main Authors: Adriaansen, J, Tas, S, Klarenbeek, P, Bakker, A, Apparailly, F, Firestein, G, Jorgensen, C, Vervoordeldonk, M, Tak, P
Format: Artigo
Language:Inglês
Published: 2005
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Extended Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755308/
https://ncbi.nlm.nih.gov/pubmed/15878906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.035063
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