Comparative intra-articular gene transfer of seven adeno-associated virus serotypes reveals that AAV2 mediates the most efficient transduction to mouse arthritic chondrocytes

Osteoarthritis (OA) is the most common arthropathy, characterized by progressive degeneration of the articular cartilage. Currently, there are no disease-modifying approaches for OA treatment. Adeno-associated virus (AAV)-mediated gene therapy has recently become a potential treatment for OA due to...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Chen, Quan, Luo, Huan, Zhou, Chengcong, Yu, Huan, Yao, Sai, Fu, Fangda, Seeley, Rebecca, Ji, Xing, Yang, Yanping, Chen, Peifeng, Jin, Hongting, Tong, Peijian, Chen, Di, Wu, Chengliang, Du, Weibin, Ruan, Hongfeng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737971/
https://ncbi.nlm.nih.gov/pubmed/33320893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243359
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