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Reduction of arthritis following intra‐articular administration of an adeno‐associated virus serotype 5 expressing a disease‐inducible TNF‐blocking agent
BACKGROUND: In the context of preclinical development, we studied the potential of intra‐articular gene delivery using a recombinant adeno‐associated virus 5 (rAAV5) encoding a chimeric human tumour necrosis factorα (TNFα) soluble receptor I linked to a mouse immunoglobulin heavy chain Fc portion (T...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955149/ https://ncbi.nlm.nih.gov/pubmed/17363402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.064519 |
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