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INTRA-ARTICULAR CLEARANCE OF LABELED DEXTRANS FROM NAIVE AND ARTHRITIC RAT KNEE JOINTS

OBJECTIVE: Determine the effects of arthritis on the trans-synovial clearance of small and large model compounds following local delivery to the knee joint in a rat model. DESIGN: Intra-articular delivery was studied in rat knee joints in an osteoarthritis model of knee joint instability (medial col...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Mwangi, Timothy K., Berke, Ian, Nieves, Eduardo H., Bell, Richard D., Adams, Samuel B., Setton, Lori A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269097/
https://ncbi.nlm.nih.gov/pubmed/29842918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.05.029
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