A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

Secreted aspartyl proteinases (Saps) from Candida albicans are encoded by a multigene family with at least nine members (SAP1 to SAP9) and are considered putative virulence factors important for the pathogenicity of this human pathogen. The role of Sap isoenzymes in the virulence of C. albicans has...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Sanglard, D, Hube, B, Monod, M, Odds, F C, Gow, N A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284117/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.9.3539-3546.1997
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