A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

Secreted aspartyl proteinases (Saps) from Candida albicans are encoded by a multigene family with at least nine members (SAP1 to SAP9) and are considered putative virulence factors important for the pathogenicity of this human pathogen. The role of Sap isoenzymes in the virulence of C. albicans has...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Sanglard, D, Hube, B, Monod, M, Odds, F C, Gow, N A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284117/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.9.3539-3546.1997
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