Candida albicans Hyphal Formation and the Expression of the Efg1-Regulated Proteinases Sap4 to Sap6 Are Required for the Invasion of Parenchymal Organs

The ability to change between yeast and hyphal cells (dimorphism) is known to be a virulence property of the human pathogen Candida albicans. The pathogenesis of disseminated candidosis involves adhesion and penetration of hyphal cells from a colonized mucosal site to internal organs. Parenchymal or...

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Main Authors: Felk, Angelika, Kretschmar, Marianne, Albrecht, Antje, Schaller, Martin, Beinhauer, Sabine, Nichterlein, Thomas, Sanglard, Dominique, Korting, Hans C., Schäfer, Wilhelm, Hube, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC128044/
https://ncbi.nlm.nih.gov/pubmed/12065511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3689-3700.2002
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