A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

Secreted aspartyl proteinases (Saps) from Candida albicans are encoded by a multigene family with at least nine members (SAP1 to SAP9) and are considered putative virulence factors important for the pathogenicity of this human pathogen. The role of Sap isoenzymes in the virulence of C. albicans has...

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Pubblicato in:	Infect Immun
Autori principali:	Sanglard, D, Hube, B, Monod, M, Odds, F C, Gow, N A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284117/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.9.3539-3546.1997
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