Monophosphoryl lipid A enhances both humoral and cell-mediated immune responses to DNA vaccination against human immunodeficiency virus type 1.

To enhance immunity induced by DNA vaccination against human immunodeficiency virus type 1 (HIV-1), we evaluated the efficacy of monophosphoryl lipid A (MPL), an adjuvant of bacterial origin. BALB/c mice were intramuscularly injected with immunogenic DNA, encoding the env and rev genes of the HIV-1(...

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Main Authors: Sasaki, S, Tsuji, T, Hamajima, K, Fukushima, J, Ishii, N, Kaneko, T, Xin, K Q, Mohri, H, Aoki, I, Okubo, T, Nishioka, K, Okuda, K
格式: Artigo
語言:Inglês
出版: 1997
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC175502/
https://ncbi.nlm.nih.gov/pubmed/9284115
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