Intranasal administration of human immunodeficiency virus type-1 (HIV-1) DNA vaccine with interleukin-2 expression plasmid enhances cell-mediated immunity against HIV-1.

DNA vaccine against human immunodeficiency virus type-1 (HIV-1) can induce substantial levels of HIV-1-specific humoral and cell-mediated immunity. To develop more potent HIV-1 DNA vaccine formulations, we used a murine model to explore the immunomodulatory effects of an interleukin-2 (IL-2) express...

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Autors principals: Xin, K Q, Hamajima, K, Sasaki, S, Honsho, A, Tsuji, T, Ishii, N, Cao, X R, Lu, Y, Fukushima, J, Shapshak, P, Kawamoto, S, Okuda, K
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364265/
https://ncbi.nlm.nih.gov/pubmed/9767429
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