Comparison of Intranasal and Intramuscular Immunization against Human Immunodeficiency Virus Type 1 with a DNA-Monophosphoryl Lipid A Adjuvant Vaccine

We compared immune responses to intranasal and intramuscular DNA vaccinations against human immunodeficiency virus type 1 with monophosphoryl lipid A (MPL) used as an adjuvant. Both routes of vaccination resulted in similar levels of cell-mediated immunity, but the intestinal secretory immunoglobuli...

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Main Authors: Sasaki, Shin, Hamajima, Kenji, Fukushima, Jun, Ihata, Atsushi, Ishii, Norihisa, Gorai, Itsuo, Hirahara, Fumiki, Mohri, Hiroshi, Okuda, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107976/
https://ncbi.nlm.nih.gov/pubmed/9453648
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