Effects of moderate renal insufficiency on pharmacokinetics of methotrexate in rheumatoid arthritis patients

OBJECTIVES—To determine the effects of impaired renal function on the pharmacokinetics of methotrexate (MTX) in rheumatoid arthritis (RA) patients.
METHODS—77 RA patients were included in this study. MTX was administered intramuscularly (7.5 to 15 mg). Subjects were divided into four groups, accordi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Bressolle, F, Bologna, C, Kinowski, J, Sany, J, Combe, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
Soggetti:
Concise Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752537/
https://ncbi.nlm.nih.gov/pubmed/9613341
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi