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Effects of moderate renal insufficiency on pharmacokinetics of methotrexate in rheumatoid arthritis patients
OBJECTIVES—To determine the effects of impaired renal function on the pharmacokinetics of methotrexate (MTX) in rheumatoid arthritis (RA) patients. METHODS—77 RA patients were included in this study. MTX was administered intramuscularly (7.5 to 15 mg). Subjects were divided into four groups, accordi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1752537/ https://ncbi.nlm.nih.gov/pubmed/9613341 |
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