Effects of moderate renal insufficiency on pharmacokinetics of methotrexate in rheumatoid arthritis patients

OBJECTIVES—To determine the effects of impaired renal function on the pharmacokinetics of methotrexate (MTX) in rheumatoid arthritis (RA) patients.
METHODS—77 RA patients were included in this study. MTX was administered intramuscularly (7.5 to 15 mg). Subjects were divided into four groups, accordi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bressolle, F, Bologna, C, Kinowski, J, Sany, J, Combe, B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1998
Pynciau:
Concise Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752537/
https://ncbi.nlm.nih.gov/pubmed/9613341
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