Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague.

The caf operon from Yersinia pestis encoding the structural subunit (caf1), the molecular chaperone (caf1M), the outer membrane anchor (caf1A), and the regulatory protein (caf1R) was cloned into Salmonella typhimurium SL3261 aroA. The recombinant Salmonella organisms were encapsulated when cultured...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Titball, R W, Howells, A M, Oyston, P C, Williamson, E D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9125581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.5.1926-1930.1997
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