Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague.

The caf operon from Yersinia pestis encoding the structural subunit (caf1), the molecular chaperone (caf1M), the outer membrane anchor (caf1A), and the regulatory protein (caf1R) was cloned into Salmonella typhimurium SL3261 aroA. The recombinant Salmonella organisms were encapsulated when cultured...

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Pubblicato in:	Infect Immun
Autori principali:	Titball, R W, Howells, A M, Oyston, P C, Williamson, E D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9125581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.5.1926-1930.1997
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