Immunogenicity of a Salmonella typhimurium aroA aroD Vaccine Expressing a Nontoxic Domain of Clostridium difficile Toxin A

The C-terminal repeat domain of Clostridium difficile toxin A harbors toxin-neutralizing epitopes and is considered to be a candidate component of a vaccine against C. difficile-associated disease (CDAD). Fourteen of the 38 C-terminal toxin A repeats (14CDTA) were cloned into pTECH-1 in frame with t...

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Autores principales: Ward, Stephen J., Douce, Gill, Figueiredo, Dayse, Dougan, Gordon, Wren, Brendan W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC115950/
https://ncbi.nlm.nih.gov/pubmed/10225867
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