Immunogenicity of a Salmonella typhimurium aroA aroD Vaccine Expressing a Nontoxic Domain of Clostridium difficile Toxin A

The C-terminal repeat domain of Clostridium difficile toxin A harbors toxin-neutralizing epitopes and is considered to be a candidate component of a vaccine against C. difficile-associated disease (CDAD). Fourteen of the 38 C-terminal toxin A repeats (14CDTA) were cloned into pTECH-1 in frame with t...

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Vydáno v:	Infect Immun
Hlavní autoři:	Ward, Stephen J., Douce, Gill, Figueiredo, Dayse, Dougan, Gordon, Wren, Brendan W.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Microbial Immunity and Vaccines
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115950/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10225867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.5.2145-2152.1999
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