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Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague.

The caf operon from Yersinia pestis encoding the structural subunit (caf1), the molecular chaperone (caf1M), the outer membrane anchor (caf1A), and the regulatory protein (caf1R) was cloned into Salmonella typhimurium SL3261 aroA. The recombinant Salmonella organisms were encapsulated when cultured...

詳細記述

保存先:
書誌詳細
出版年:Infect Immun
主要な著者: Titball, R W, Howells, A M, Oyston, P C, Williamson, E D
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175242/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9125581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.5.1926-1930.1997
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