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Mechanism of action of novel NO-releasing furoxan derivatives of aspirin in human platelets
1. Incorporation of a nitric oxide (NO)-releasing moiety in aspirin can overcome its gastric side effects. 2. We investigated the NO-release patterns and antiplatelet effects of novel furoxan derivatives of aspirin (B8 and B7) in comparison to existing antiplatelet agents. 3. Cyclooxygenase (COX) ac...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751793/ https://ncbi.nlm.nih.gov/pubmed/16702997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706743 |
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