Leishmanicidal Activities of Novel Synthetic Furoxan and Benzofuroxan Derivatives

A novel series of furoxan (1,2,5-oxadiazole 2-oxide) (compounds 3, 4a and -b, 13a and -b, and 14a to -f) and benzofuroxan (benzo[c][1,2,5]oxadiazole 1-oxide) (compounds 7 and 8a to -c) derivatives were synthesized, characterized, and evaluated for in vitro activity against promastigote and intracell...

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Autors principals: Dutra, Luiz Antônio, de Almeida, Letícia, Passalacqua, Thais G., Reis, Juliana Santana, Torres, Fabio A. E., Martinez, Isabel, Peccinini, Rosangela Gonçalves, Chin, Chung Man, Chegaev, Konstantin, Guglielmo, Stefano, Fruttero, Roberta, Graminha, Marcia A. S., dos Santos, Jean Leandro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Chemistry; Biosynthesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136072/
https://ncbi.nlm.nih.gov/pubmed/24913171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00052-14
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