Leishmanicidal Activities of Novel Synthetic Furoxan and Benzofuroxan Derivatives

A novel series of furoxan (1,2,5-oxadiazole 2-oxide) (compounds 3, 4a and -b, 13a and -b, and 14a to -f) and benzofuroxan (benzo[c][1,2,5]oxadiazole 1-oxide) (compounds 7 and 8a to -c) derivatives were synthesized, characterized, and evaluated for in vitro activity against promastigote and intracell...

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Autori principali: Dutra, Luiz Antônio, de Almeida, Letícia, Passalacqua, Thais G., Reis, Juliana Santana, Torres, Fabio A. E., Martinez, Isabel, Peccinini, Rosangela Gonçalves, Chin, Chung Man, Chegaev, Konstantin, Guglielmo, Stefano, Fruttero, Roberta, Graminha, Marcia A. S., dos Santos, Jean Leandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Chemistry; Biosynthesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136072/
https://ncbi.nlm.nih.gov/pubmed/24913171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00052-14
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