Clinical isolate of herpes simplex virus type 2 that induces a thymidine kinase with altered substrate specificity.

In vitro and in vivo studies were done on a herpes simplex virus type 2 strain recovered from a patient on acyclovir (ACV) which was ACV resistant but expressed thymidine (dThd) kinase (EC 2.7.1.21) activity. Plaque-purified clones derived from the original clinical sample were heterogeneous with re...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Ellis, M N, Keller, P M, Fyfe, J A, Martin, J L, Rooney, J F, Straus, S E, Lehrman, S N, Barry, D W
Формат: Artigo
Язык:Inglês
Опубликовано: 1987
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC174881/
https://ncbi.nlm.nih.gov/pubmed/2821890
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы