Clinical isolate of herpes simplex virus type 2 that induces a thymidine kinase with altered substrate specificity.
In vitro and in vivo studies were done on a herpes simplex virus type 2 strain recovered from a patient on acyclovir (ACV) which was ACV resistant but expressed thymidine (dThd) kinase (EC 2.7.1.21) activity. Plaque-purified clones derived from the original clinical sample were heterogeneous with re...
محفوظ في:
| الحاوية / القاعدة: | Antimicrob Agents Chemother |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1987
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2821890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.7.1117 |
| الوسوم: |
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