Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange

Regional alveolar hypoxia causes local vasoconstriction in the lung, shifting blood flow from hypoxic to normoxic areas, thereby maintaining gas exchange. This mechanism is known as hypoxic pulmonary vasoconstriction (HPV). Disturbances in HPV can cause life-threatening hypoxemia whereas chronic hyp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Weissmann, Norbert, Dietrich, Alexander, Fuchs, Beate, Kalwa, Hermann, Ay, Mahmut, Dumitrascu, Rio, Olschewski, Andrea, Storch, Ursula, Mederos y Schnitzler, Michael, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo, Pinkenburg, Olaf, Seeger, Werner, Grimminger, Friedrich, Gudermann, Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748182/
https://ncbi.nlm.nih.gov/pubmed/17142322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606728103
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