Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction

BACKGROUND: Acute respiratory disorders may lead to sustained alveolar hypoxia with hypercapnia resulting in impaired pulmonary gas exchange. Hypoxic pulmonary vasoconstriction (HPV) optimizes gas exchange during local acute (0-30 min), as well as sustained (> 30 min) hypoxia by matching blood pe...

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Autors principals: Ketabchi, Farzaneh, Ghofrani, Hossein A, Schermuly, Ralph T, Seeger, Werner, Grimminger, Friedrich, Egemnazarov, Bakytbek, Shid-Moosavi, S Mostafa, Dehghani, Gholam A, Weissmann, Norbert, Sommer, Natascha
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306743/
https://ncbi.nlm.nih.gov/pubmed/22292558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-7
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