Activity of purine analogs against Leishmania donovani in vivo.
The dose of orally administered 9-deazainosine calculated to suppress 50% of Leishmania donovani amastigotes in hamster livers was 19 mg/kg (body weight) per day; 96 to 99% of Leishmania organisms were eliminated from the liver and spleen of squirrel monkeys by 50 mg/kg per day. Because these activi...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3566235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.1.111 |
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