Activity of purine analogs against Leishmania donovani in vivo.

The dose of orally administered 9-deazainosine calculated to suppress 50% of Leishmania donovani amastigotes in hamster livers was 19 mg/kg (body weight) per day; 96 to 99% of Leishmania organisms were eliminated from the liver and spleen of squirrel monkeys by 50 mg/kg per day. Because these activi...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Berman, J D, Hanson, W L, Lovelace, J K, Waits, V B, Jackson, J E, Chapman, W L, Klein, R S
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1987
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3566235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.1.111
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