Microtubule-disrupting agents inhibit nitric oxide production in murine peritoneal macrophages stimulated with lipopolysaccharide or paclitaxel (Taxol).

Paclitaxel (Taxol), a yew-derived antimitotic agent which binds to microtubules, can mimic certain effects of lipopolysaccharide (LPS) on macrophages from LPS responder mouse strains. The production of nitric oxide (NO) by the peritoneal macrophages of LPS responder C3H/HeN mice stimulated with taxo...

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Dettagli Bibliografici
Autori principali: Kirikae, T, Kirikae, F, Oghiso, Y, Nakano, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC174233/
https://ncbi.nlm.nih.gov/pubmed/8757879
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