Lipopolysaccharide and monophosphoryl lipid A differentially regulate interleukin-12, gamma interferon, and interleukin-10 mRNA production in murine macrophages.

Monophosphoryl lipid A (MPL) is a nontoxic derivative of the lipid A region of lipopolysaccharide (LPS) that is being developed as both an adjuvant and prophylactic drug for septic shock. We compared the ability of LPS and MPL to induce interleukin-10 (IL-10), IL-12 p35, IL-12 p40, gamma interferon...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Salkowski, C A, Detore, G R, Vogel, S N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.8.3239-3247.1997
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