Microtubule-disrupting agents inhibit nitric oxide production in murine peritoneal macrophages stimulated with lipopolysaccharide or paclitaxel (Taxol).

Paclitaxel (Taxol), a yew-derived antimitotic agent which binds to microtubules, can mimic certain effects of lipopolysaccharide (LPS) on macrophages from LPS responder mouse strains. The production of nitric oxide (NO) by the peritoneal macrophages of LPS responder C3H/HeN mice stimulated with taxo...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Kirikae, T, Kirikae, F, Oghiso, Y, Nakano, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8757879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.8.3379-3384.1996
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