Microtubule-disrupting agents inhibit nitric oxide production in murine peritoneal macrophages stimulated with lipopolysaccharide or paclitaxel (Taxol).

Paclitaxel (Taxol), a yew-derived antimitotic agent which binds to microtubules, can mimic certain effects of lipopolysaccharide (LPS) on macrophages from LPS responder mouse strains. The production of nitric oxide (NO) by the peritoneal macrophages of LPS responder C3H/HeN mice stimulated with taxo...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Kirikae, T, Kirikae, F, Oghiso, Y, Nakano, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8757879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.8.3379-3384.1996
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