Allelic exchange mutagenesis of nixA in Helicobacter pylori results in reduced nickel transport and urease activity.

Helicobacter pylori, an etiologic agent of gastritis and peptic ulceration in humans, synthesizes urease, a nickel metalloenzyme, as its most abundant protein. NixA, a high-affinity nickel transport protein, allows synthesis of catalytically active urease when coexpressed with H. pylori urease in an...

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Publicado en:	Infect Immun
Autores principales:	Bauerfeind, P, Garner, R M, Mobley, L T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698529/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2877-2880.1996
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