Allelic exchange mutagenesis of nixA in Helicobacter pylori results in reduced nickel transport and urease activity.
Helicobacter pylori, an etiologic agent of gastritis and peptic ulceration in humans, synthesizes urease, a nickel metalloenzyme, as its most abundant protein. NixA, a high-affinity nickel transport protein, allows synthesis of catalytically active urease when coexpressed with H. pylori urease in an...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Infect Immun |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
1996
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698529/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2877-2880.1996 |
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