Substitution of cysteine 192 in a highly conserved Streptococcus pyogenes extracellular cysteine protease (interleukin 1beta convertase) alters proteolytic activity and ablates zymogen processing.

Eitemau Tebyg

• Fibrinogen Cleavage by the Streptococcus pyogenes Extracellular Cysteine Protease and Generation of Antibodies That Inhibit Enzyme Proteolytic Activity
  gan: Matsuka, Yury V., et al.
  Cyhoeddwyd: (1999)
• A PROTEOLYTIC ENZYME OF STREPTOCOCCUS ZYMOGENES
  gan: Grutter, Frederick H., et al.
  Cyhoeddwyd: (1955)
• Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.
  gan: Kapur, V, et al.
  Cyhoeddwyd: (1993)
• Activation of a 66-kilodalton human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease.
  gan: Burns, E H, et al.
  Cyhoeddwyd: (1996)
• Different forms of streptolysin O produced by Streptococcus pyogenes and by Escherichia coli expressing recombinant toxin: cleavage by streptococcal cysteine protease.
  gan: Pinkney, M, et al.
  Cyhoeddwyd: (1995)