Genetic Inactivation of an Extracellular Cysteine Protease (SpeB) Expressed by Streptococcus pyogenes Decreases Resistance to Phagocytosis and Dissemination to Organs

Streptococcal pyrogenic exotoxin B (SpeB), a conserved cysteine protease expressed by virtually all Streptococcus pyogenes strains, has recently been shown to be an important virulence factor (S. Lukomski, S. Sreevatsan, C. Amberg, W. Reichardt, M. Woischnik, A. Podbielski, and J. M. Musser, J. Clin...

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Detalhes bibliográficos
Main Authors: Lukomski, Slawomir, Burns, Eugene H., Wyde, Philip R., Podbielski, Andreas, Rurangirwa, Jacqueline, Moore-Poveda, Donna K., Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Molecular and Cellular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107969/
https://ncbi.nlm.nih.gov/pubmed/9453640
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