Characterization of recombinant tetanus toxin derivatives suitable for vaccine development.
Recombinant derivatives of tetanus toxin (TeTx) were isolated and used to immunize mice. Recombinant TeTx light chain, a derivative of fragment C that had lost the ability to bind neurons, and a recombinant TeTx holotoxoid that could protect mice against TeTx challenge were identified.
I tiakina i:
| I whakaputaina i: | Infect Immun |
|---|---|
| Ngā kaituhi matua: | , , , , , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
American Society for Microbiology (ASM)
1995
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7622252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.8.3218-3221.1995 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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