Characterization of recombinant tetanus toxin derivatives suitable for vaccine development.

Recombinant derivatives of tetanus toxin (TeTx) were isolated and used to immunize mice. Recombinant TeTx light chain, a derivative of fragment C that had lost the ability to bind neurons, and a recombinant TeTx holotoxoid that could protect mice against TeTx challenge were identified.

Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Figueiredo, D, Turcotte, C, Frankel, G, Li, Y, Dolly, O, Wilkin, G, Marriott, D, Fairweather, N, Dougan, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7622252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.8.3218-3221.1995
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!