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DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli

We investigated the global changes in mRNA abundance in Escherichia coli elicited by various perturbations of tryptophan metabolism. To do so we printed DNA microarrays containing 95% of all annotated E. coli ORFs. We determined the expression profile that is predominantly dictated by the activity o...

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Bibliographic Details
Main Authors: Khodursky, Arkady B., Peter, Brian J., Cozzarelli, Nicholas R., Botstein, David, Brown, Patrick O., Yanofsky, Charles
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17313/
https://ncbi.nlm.nih.gov/pubmed/11027315
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