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DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli

We investigated the global changes in mRNA abundance in Escherichia coli elicited by various perturbations of tryptophan metabolism. To do so we printed DNA microarrays containing 95% of all annotated E. coli ORFs. We determined the expression profile that is predominantly dictated by the activity o...

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Detalhes bibliográficos
Main Authors: Khodursky, Arkady B., Peter, Brian J., Cozzarelli, Nicholas R., Botstein, David, Brown, Patrick O., Yanofsky, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17313/
https://ncbi.nlm.nih.gov/pubmed/11027315
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