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Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.

Two mutants defective in herpes simplex virus-encoded ribonucleotide reductase activity exhibited the novel phenotype of hypersensitivity to acyclovir, aphidicolin, and to a lesser extent, phosphonoacetic acid. These results have implications for acyclovir resistance and the development of drugs tha...

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Bibliografiske detaljer
Main Authors: Coen, D M, Goldstein, D J, Weller, S K
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC172665/
https://ncbi.nlm.nih.gov/pubmed/2552912
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